辐射防护2012,Vol.32Issue(1):28-33,6.
槲皮素和17-AAG对大鼠外周血淋巴细胞辐射敏感性的影响研究
Effect of Quercetin and 17-AAG on Radiosensitivity of Rat Peripheral Blood Lymphocyte
摘要
Abstract
To investigate the effect of quercetin and 17-AAG on proliferation and on radiosensitivity of blood lymphocyte cells.CCK-8 assay is performed to evaluate the cytotoxicity of Quercetin on proliferation of blood lymphocyte cells.CCK-8 assay employed to observe its effects on the radiosensitivity of the cells quantified by calculating the sensitive enhancement ratio(SER).CCK-8 results showed that the inhibition of Quercetin on the cells was the dose-dependent and time-dependent,and the results of assay showed the inhibition of 17-AAG on blood lymphocyte cells was the dose-dependent and timedependent.The study showed that Quercetin and 17-AAG have no effect on the radiosensitivity of the blood lymphocyte cells.关键词
槲皮素/17-AAG/大鼠外周血淋巴细胞/辐射敏感性/细胞增殖Key words
quercetin/17-AAG/radiosensitivity/proliferation/blood lymphocyte cells分类
医药卫生引用本文复制引用
褚薛刚,洪承皎,张保国..槲皮素和17-AAG对大鼠外周血淋巴细胞辐射敏感性的影响研究[J].辐射防护,2012,32(1):28-33,6.基金项目
国家自然科学基金资助项目 ()