分析测试学报2011，Vol.30Issue(12)：1372-1376,5.DOI:10.3969/j.issn.1004-4957.2011.12.008
QuEChERS/高效液相色谱测定食品中17种邻苯二甲酸酯
Determination of 17 Phthalate Esters in Food by QuEChERS/High Performance Liquid Chromatography
摘要
Abstract
A QuEChERS with high performance liquid chromatographic ( HPLC) method was developed for the determination of 17 phthalate esters ( PAEs), e.g. DMEP, DMP, DEEP, DEP, DPhP, BBP, DIBP, DBP, DBEP, DPP, DCHP, BMPP, DHXP, DEHP, DNOP, DINP and DNP, in food samples. The targeted compounds were extracted with acetonitrile, and purified by PSA-based QuEChERS (50 mg PSA and 150 mg MgSO4). The extract were separated on a Ci8 column with mobile phase composed of water and acetonitrile by gradient elution at a flow rate of 1. 0 mL/min. The UV detection wavelength was set at 224 nm. Under the optimal conditions, the calibration curves of phthalate esters were linear in the ranges of 0. 5 - 10 mg/L for DINP and 0. 05 - 10 mg/L for the others with correlation coefficients ( r ) more than 0. 99. The average recoveries of 17 analytes from 5 kinds of food matrixes were in the range of 70% - 120% with RSDs ( n = 6 ) less than 15% . The detection limits ( LODs, S/N = 3 ) of phthalate esters were 0. 001 - 0. 02 mg/L and the quantitation limits (LOQs, S/N = 10) were 0. 05 - 0. 5 mg/kg. The proposed procedure was applied in the analysis of 432 real samples from Xiamen, Fujian province( China) , in which 18 positive samples were found. The proposed method was simple and accurate, and could be applicable for the routine analysis of monitoring PAEs residues in foodstuffs.关键词
邻苯二甲酸酯/QuEChERS/高效液相色谱/食品Key words
phthalate esters (PAEs)/ QuEChERS/ high performance liquid chromatography (HPLC) /food分类
化学化工引用本文复制引用
施雅梅,徐敦明,周昱,周爽,方恩华,严丽娟,李文斌,孔凡霞..QuEChERS/高效液相色谱测定食品中17种邻苯二甲酸酯[J].分析测试学报,2011,30(12):1372-1376,5.基金项目
SN行业标准制修订计划项目(2011B341J) （2011B341J）
厦门出入境检验检疫局科技项目(2011XK005) （2011XK005）
