高等学校化学学报2011，Vol.32Issue(12)：2733-2738,6.
新型尾式组氨酸卟啉的合成及性质
Synthesis and Characterization of New Tailed Histidine-Linked Porphyrins
摘要
Abstract
A new histidine-linked porphyrin(l) and different transition metalloporphyrins[Zn(2) , Co(3) , Fe(4) , Mn(5) ] were prepared, purified and characterized by means of elemental analysis, IR, UV-Vis and 1H NMR. The correlation between the structures of the complexes and their ' H NMR, IR, UV spectra was discussed and their specific spectra were explained. Their fluorescence characters were studied with the aid of fluorescence spectra and the lowest energy conformation were chosen with 100 ps molecular dynamic simulation. The fluorescence intensity and the quantum yield of porphyrin 1 were low because of the electron-withdrawing group on peripheral porphyrin ring. The fluorescence intensity and the quantum yield of metallopor-phyrin 2 were much weaker than those of the corresponding metal-free porphyrin 1 because zinc weakened the fluorescence radiation. Fluorescence signals had not been detected for metalloporphyrins 3-5 under the same experimental conditions because of the fluorescence quenching. The mininal energy conformations and binding mode of four host-gust systems were obtained by molecular minimize and quantum chemistry. The four host-guest complexes were investigated to predicte the coordinate bond on four transition metal.关键词
氨基酸/卟啉/金属卟啉/荧光/分子力学模拟Key words
Amino acid/ Porphyrin/ Metalloporphyrin/ Fluorescence/ Molecular dynamic simulation分类
化学化工引用本文复制引用
单凝,连文慧,王彬彬,孙园园,郑文琦,于苗,师同顺..新型尾式组氨酸卟啉的合成及性质[J].高等学校化学学报,2011,32(12):2733-2738,6.基金项目
国家自然科学基金(批准号:20801022)资助. （批准号:20801022）
