高等学校化学学报2011，Vol.32Issue(12)：2748-2751,4.
d(C4)相关序列形成四分子i-Motif结构的电喷雾质谱研究
Electrospray Ionization Mass Spectrometry Studies of Tetramolecular i-Motif Structures Formed by d(C4) Related Sequences
摘要
Abstract
A series of cytosine-rich DNA sequence d(C4) related DNA strands, including d(C4) , d(TC4) , d(AC4) , d(T2C4) , d(A2C4) , d(C4T) , d(C4A) and d(TC4T) , was designed in this study, and the tetramolecular ions formed by the sequences were measured with electrospray ionization mass spectrometry. The goal is to obtain the information on the formation of the tetramolecular I-motif influenced by adenine ( A) and thymine(T) that present at 5' and 3' ends of d( C4). The results showed that when A base or T base was added at 5' end of d ( C4) , it is easier for the sequence to form tetramolecular ion, especially for thymine, when adding two A or T bases to d(C4) , the sequence generates higher abundant of the tetramolecualr ion.关键词
DNA i-motif结构/电喷雾质谱/d(C4)相关序列/非共价相互作用Key words
DNA I-motif structure/ Electrospray ionization mass spectrometry/ d ( C4 ) related sequence/ Non-covalent interaction分类
化学化工引用本文复制引用
秦玉娇,魏士刚,王晓录,杨帆,汪兵,国新华..d(C4)相关序列形成四分子i-Motif结构的电喷雾质谱研究[J].高等学校化学学报,2011,32(12):2748-2751,4.基金项目
国家自然科学基金(批准号:20575066,20975044)资助. （批准号:20575066,20975044）
