高等学校化学学报2011，Vol.32Issue(12)：2891-2895,5.
胶原液晶膜的制备及对细胞生长的影响
Effects of Collagen Liquid Crystalline Films on Cell Culture
摘要
Abstract
A series of biomimetic collagen films was prepared. The texture and topological structure of collagen films were studied by polarizing optical microscopy ( POM ) , scanning electron microscopy ( SEM ) and atomic force microscopy (AFM). The relationship between collagen membranes and 3T3 cells was studied by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) method and cytoskeleton fluorescence staining. The results show that the collagen liquid crystal (LC) membranes present continuously twisting orientations in cholesteric phases characterized by typical series of arced patterns. Compared with the non-LC membranes , LC membranes not only could promote the cell' s adhesion and proliferation, but also the LC topological structure had a contact guide effect to 3T3 cells.关键词
胶原/液晶/拓扑结构/接触引导Key words
Collagen/ Liquid crystal/ Topological structure/ Contact guide分类
化学化工引用本文复制引用
唐敏健,丁珊,闵翔,焦延鹏,周长忍,李红..胶原液晶膜的制备及对细胞生长的影响[J].高等学校化学学报,2011,32(12):2891-2895,5.基金项目
国家自然科学基金(批准号:31070852)和教育部博士学科点基金(批准号:200805590001)资助. （批准号:31070852）
