高等学校化学学报2012,Vol.33Issue(1):210-214,5.DOI:10.3969/j.issn.0251-0790.2012.01.036
一种光功能有机纳米粒子的制备及细胞毒性评价
Evaluation of the Cytotoxicity About Photic Organic Nanoparticles
摘要
Abstract
The cytotoxicity about organic nanoparticles which has the function of two-photon fluorescent probe 2,5 ,2',5'-tetra(4'-N,N-diphenylaminostyryl)biphenyl(DPA-TSB) was studied. The physiological activity of stomach cancer cells after englobing the nanoparticle was detected by the methods of WAT-1, Lactate dehydro-genase( LDH) and flow cytometry. The results show that the stomach cancer cells can live well when the concentration of the nanoparticles is below 12 μg/mL, which suggests that the nanoparticles have the property of good biological security.关键词
有机纳米粒子/细胞毒性/流式细胞术Key words
Organic nanoparticles/ Cytotoxicity/ Flow cytometry分类
化学化工引用本文复制引用
李晓东,杨淑敏,徐红,马於光..一种光功能有机纳米粒子的制备及细胞毒性评价[J].高等学校化学学报,2012,33(1):210-214,5.基金项目
国家自然科学基金(批准号:51173066)资助. (批准号:51173066)