摘要
Abstract
Objective:To explore whether anti-mullerian hormone (AMH) measurement in the serum could be a marker for diagnosis of polycystic ovary syndrome (PCOS). Methods: Serum AMH was measured with immunoassay in a cohort of 75 PCOS patients and 86 controls,and follicle number was estimated by ultrasound scanning. Results:Serum AMH levels were 4-fold higher in PCOS patients than in control group [ (8.21±2.32) mg/L vs. (2.39±1.29) mg/L] ,and were significantly related to the follicle number in the two groups. In PCOS patients, AMH concentrations correlated with the number of ovarian follicles,testosterone 、LH and LH/FSH(r= 0.489,0.215,0.312 and 0.256,P<0.05) ,but not related with FSH、E2 PRL and BMI (r=0.12,0.19,0.10 and 0.16,P>0.05).ConcIusions:The serum AMH level was a marker which may be used for diagnosis of the PCOS.关键词
抗苗勒管激素/多囊卵巢综合征/卵泡刺激素/雌二醇/睾酮Key words
Anti-mullerian hormone/Polycystic ovary syndrome/Follicle stimulating hormone/Estradiol/Testosterone
