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孤立性轻度侧脑室增宽胎儿的产前诊断及预后

宋花蕾 方群 陈宝江 罗艳敏 陈涌珍 陈筠虹

国际妇产科学杂志2012,Vol.39Issue(1):79-81,3.
国际妇产科学杂志2012,Vol.39Issue(1):79-81,3.

孤立性轻度侧脑室增宽胎儿的产前诊断及预后

Prenatal Diagnosis and Prognosis of Isolated Mild Fetal Cerebral Ventriculomegaly

宋花蕾 1方群 2陈宝江 2罗艳敏 2陈涌珍 2陈筠虹2

作者信息

  • 1. 256603 山东省滨州市,滨州医学院附属医院妇产科
  • 2. 广州,中山大学附属第一医院妇产科胎儿医学中心
  • 折叠

摘要

Abstract

Objective: To investigate the results of prenatal diagnosis and prognosis of isolated mild ventriculomegaly fetuses. Methods:Chromosomal karyotypes were retrospectively investigated in sixty one singleton fetuses with isolated mild ventriculomegaly. The outcome of fetuses was acquired through regular follow-up. Results: In 61 cases of isolated mild ventriculomegaly, 3 (4.92%) chromosomal aberrations were detected, including 2 Down syndrome and 1 trisomy sex chromosome. In 50 cases which the IgM of toxoplasma, cytomegalovirus and rubella virus was detected, one case was positive with rubella virus IgM. Follow-up was successful in 55 cases, 8 were terminated because of various causes, including 3 chromosomal aberrations and 1 rubella IgM positive case. In 47 alive cases, 1 was found to have multi-maformation after birth, 1 died in neonatal period, 2 with developmental retardation, 43 cases (91.49% ) with normal development. Conclusions: Prenatal diagnosis is necessary for the fetuses with isolated mild ventriculomegaly. Apart from chromosome aberration and congenital infection, most of isolated mild ventriculomegaly fetuses have good prognosis.

关键词

超声检查,产前/胎儿/侧脑室/产前诊断/染色体畸变/唐氏综合征

Key words

Ultrasonography, prenatal/ Fetus (Lateral ventricles/ Prenatal diagnosis/ Chromosome aberrations/ Down syndrome

引用本文复制引用

宋花蕾,方群,陈宝江,罗艳敏,陈涌珍,陈筠虹..孤立性轻度侧脑室增宽胎儿的产前诊断及预后[J].国际妇产科学杂志,2012,39(1):79-81,3.

国际妇产科学杂志

OACSTPCD

1674-1870

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