中国妇幼健康研究2012，Vol.23Issue(1)：20-22,3.DOI:10.3969/j.issn.1673-5293.2012.01.007
西安市城区孕妇维生素D缺乏对新生儿影响的调查研究
Effect of vitamin D deficiency among urban pregnant women on their neonates in Xi'an
王晓燕 1刘黎明 2李亚芙1
作者信息
- 1. 西安交通大学医学院第一附属医院,陕西,西安,710061
- 2. 西安市第四医院,陕西,西安,710004
- 折叠
摘要
Abstract
To investigate the nutritional status of vitamin D of urban pregnant women in Xi' an and their neonates and analyze related factors, so as to study the prevalence and influencing factors of vitamin D deficiency in them. Methods From January to February and from August to September in 2011, 182 pregnant women and their neonates delivered in NO. 4 Hospital in Xi an were enrolled in the study. Their basic information and the intake of vitamin D during pregnancy were obtained with questionnaires. Samples of maternal venous blood and cord blood were collected on the day of delivery, and the serum concentrations of 25( OH ) D, alkaline phosphatase, calcium and phosphorus were measured. A general check up was given to the neonates and the results were recorded. Results The concentration of 25( OH ) D in cord blood and maternal serum was ( 36. 76 ± 16. 92 ) nmol/L and ( 38. 54 ± 17. 18 ) nmol/L, respectively, and there was a significant positive correlation between them ( r =0. 794, P <0. 001 ). The concentration of 25( OH ) D in cord blood of neonates born in summer and autumn [ ( 39. 23 ± 17. 11 )nmol/L ] was significantly higher than that in winter and spring [ ( 34. 01 ±16. 38 )nmol/L ], and the difference was statistically significant ( t =2.08,P<0.0 ). If 25( OH ) D <50nmol/L was regarded as vitamin D deficiency, 88.46% of pregnant women and 91.20% of neonates were involved. Conclusion The prevalence of vitamin D deficiency in pregnant women and neonates in Xi an is relatively high, and nutritional status of vitamin D in urban pregnant women determines that of neonates. Vitamin D supplementation during pregnancy is needed to improve vitamin D nutritional status of both pregnant women and neonates.关键词
新生儿/孕妇/25羟维生素D/维生素D缺乏Key words
neonate/ pregnant woman /25( OH ) D/ vitamin D deficiency分类
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王晓燕,刘黎明,李亚芙..西安市城区孕妇维生素D缺乏对新生儿影响的调查研究[J].中国妇幼健康研究,2012,23(1):20-22,3.
