国际口腔医学杂志2012，Vol.39Issue(2)：257-259,264,4.DOI:10.3969/j.issn.1673-5749.2012.C2.034
表观遗传修饰和牙周病的相关性
Association between epigenetic modification and periodontal diseases
雷丹 1姜苏1
作者信息
- 1. 四川大学华西口腔医院牙周科 成都610041
- 折叠
摘要
Abstract
Periodontitis is a multifactorial infection characterized by inflammation and destruction of tooth supporting tissues, the main cause of tooth lost. The pathogenesis is complex. Not only the periodontal pathogens and its metabolites damage the tooth supporting tissues directly, but also trigger immune response. Cytokines are pro-ducted during the immune response. In recent years, some researches demonstrated that the expressing of cytokines gene was regulated by epigenetic modification. Owing to cytokines, epigenetic modification has something to do with the periodontitis. In this review, the epigenetic modification involved in periodontitis and research progress were discussed.关键词
表观遗传修饰/DNA甲基化/牙周病/炎症/细胞因子Key words
epigenetic modification/ DNA methylation/ periodontitis/ inflammation/ cytokine分类
医药卫生引用本文复制引用
雷丹,姜苏..表观遗传修饰和牙周病的相关性[J].国际口腔医学杂志,2012,39(2):257-259,264,4.
