国际口腔医学杂志2012，Vol.39Issue(2)：260-264,5.DOI:10.3969/j.issn.1673-5749.2012.02.035
苯妥英钠性牙龈增生的病理机制
Pathomechanism of phenytoin-induced gingival over-growth
肖娟 1赵慧1
作者信息
- 1. 四川大学华西口腔医院种植科 成都610041
- 折叠
摘要
Abstract
Phenytoin sodium is widely used to cure antiepileptic, trigeminal neuralgia, sciatica, paroxysmal choreoathetosis, myotonia, arrhythmia, hypertension and so, but a common and well-known adverse effect of its administration is gingival over-growth which may influence the aesthetics and oral function. The pathogenesis of Phenytoin sodium-induced gingival over-growth is not very clear now. This review summarized the mechanism of Phenytoin sodium-induced gingival over-growth, fibroblast cell proliferation and programmed cell death, collagen homeostasis, extracellular matrix accumulation and inflammation mechanism.关键词
苯妥英钠/胶原/牙龈增生/炎症Key words
Phenytoin sodium/ collagen/ gingival over-growth/ inflammation分类
生物科学引用本文复制引用
肖娟,赵慧..苯妥英钠性牙龈增生的病理机制[J].国际口腔医学杂志,2012,39(2):260-264,5.
