国际病理科学与临床杂志2011，Vol.31Issue(6)：480-482,3.DOI:10.3969/j.issn.1673-2588.2011.12.005
伊洛前列素治疗儿童先天性心脏病术后肺动脉高压对血液流变学的影响
Influence of iloprost on hemorheology of congenital heart disease with pulmonary hypertension in children
罗金文 1刘平波 1周文武 1黄鹏 1陈仁伟1
作者信息
- 1. 湖南省儿童医院心胸外科,长沙410001
- 折叠
摘要
Abstract
Objective To determine the change in hemorheology index with or without inhalation of iloprost for children with pulmonary hypertension secondary to congenital heart disease. Methods Altogether 10 children with pulmonary hypertension secondary to congenital heart disease who did not receive the iloprost inhalation treatment and 10 children with the same condition who received the ilporost inhalation treatment were randomly selected for our study. Children aged from 0 to 14. Hemorheology instrument was used to measure the change in hemorheology index in 2 groups. Re-SultS Compared with children without inhalation of iloprost, erythrocyte aggregation and blood yield stress decreased significantly, erythrocyte deformation index increased significantly 24 hours after children inhalated iloprost. There was no significant difference in hemorheology index between the non-inhalation groups at the point when children went into ICU and 24 h later. Conclusion Inhalation of iloprost can obviously improve the hemorheology properties in children with pulmonary hypertension secondary to congenital heart disease.关键词
伊洛前列素/肺动脉高压/血液流变学Key words
iloprost/pulmonary hypertension/hemorheology引用本文复制引用
罗金文,刘平波,周文武,黄鹏,陈仁伟..伊洛前列素治疗儿童先天性心脏病术后肺动脉高压对血液流变学的影响[J].国际病理科学与临床杂志,2011,31(6):480-482,3.
