广西医科大学学报2011，Vol.28Issue(5)：700-702,3.
早期目标液体复苏对脑死亡血流动力学及氧代谢的影响
EFFECTS OF EARLY GOAL-DIRECTED FLUID RESUSCITATION ON HEMODYNAMICS AND OXYGEN METABOLISM AFTER BRAIN DEATH
摘要
Abstract
Objective:To investigate the effects of early goal-directed treatment of fluid resuscitation on he-modynamics and oxygen metabolism after brain death. Methods: Thirty-two patients determined brain death in the first time were carried out goal-oriented treatment of fluid resuscitation in early 3 h after brain death. Radial artery was cannulated and Swan-Ganz catheter was placed via right internal jugular vein. The cardiac index (CD, mean pulmonary artery pressure (MPAP), pulmonary artery wedge pressure (PAWP), central venous pressure (CVP), systemic vascular resistance (SVR), pulmonary vascular resistance (PVR), oxygen supply (DO2), oxygen consumption (VO2), oxygen extraction rate (ERO2), arterial blood lactate ( ABL) and mixed venous oxygen saturation (SvO2) were measured before the fluid resuscitation (To), 3 h after fluid resuscitation (Ti ), 6 h after fluid resuscitation (T2), 12 h after the first judge of brain death (T3). Results:Compared with T0, MAP, CVP, PCWP, PAP, CI, SVR, PVP, DO2, VO2, SvO2 were significantly increased while ERO2, ABL were decreased after goal-oriented treatment of fluid resuscitation ( P <0. 05 or P <0. 01). Conclusion: There are hemodynamic and oxygen metabolic disorders in the early stage after brain death. The early goal-directed therapy of fluid resuscitation can effectively maintain hemodynamic stability, and improve the oxygen supply-demand balance of tissue and organs.关键词
脑死亡/血流动力学/氧代谢Key words
brain death/ hemodynamics/ oxygen metabolism分类
医药卫生引用本文复制引用
文宁,李壮江,张素斌,秦科,孙煦勇,董建辉,陈文斗,农江,赖彦华,聂峰..早期目标液体复苏对脑死亡血流动力学及氧代谢的影响[J].广西医科大学学报,2011,28(5):700-702,3.基金项目
广西壮族自治区科技攻关项目(No.0719006-2-7) （No.0719006-2-7）
广西自然科技基金(No.桂科自0728252) （No.桂科自0728252）
