郑州大学学报（医学版）2011，Vol.46Issue(6)：900-903,4.
分化人脑胶质瘤干细胞的放疗耐受性
Radiation therapy resistance of differential human brain glioma stem cell
摘要
Abstract
Aim: To compare the different doses of radio ray 's therapeutic effects on human brain glioma stem cells (CSC) and glioma cells and explore the relationship between radiotherapy resistance and differential phases of glioma stem cell. Methods:GSC were isolated from glioma, and meanwhile induced into normal differential glioma cells. GSC and differential glioma cells were treated with 0,2,3,5,8,12 Gy 6 MV X ray,and further cultured for 72 h. The proliferation of GSC and differential glioma cells were tested by MTT. Results: The glioma cells derived from GSC were sensitive to radiation therapy, in a dose dependent manner( F = 125. 971 ,P <0. 001). Conclusion: The glioma cells derived from GSC are more sensitive to radiation therapy than GSC.关键词
人脑胶质瘤干细胞/干细胞分化/放射治疗Key words
human brain glioma stem cell/stem cell differentiation/radiation therapy分类
医药卫生引用本文复制引用
李远,关方霞,杨波,胡祥,杜英,焦红亮,田毅..分化人脑胶质瘤干细胞的放疗耐受性[J].郑州大学学报（医学版）,2011,46(6):900-903,4.基金项目
2009 郑州大学研究生科学基金资助项目 C3210 （）
