郑州大学学报（医学版）2012，Vol.47Issue(2)：223-225,3.DOI:10.3969/j.issn.1671-6825.2012.02.025
河南汉族14个Y-STR基因位点单倍型的遗传多态性
14 Y-STR loci haplotype genetic polymorphism in Henan Han population
杨洪毅 1徐朝阳 1宋丽君 2肖海 1李晓文1
作者信息
- 1. 郑州大学基础医学院细胞生物学与医学遗传学教研室,郑州,450001
- 2. 北京康辰药业有限公司,北京,101500
- 折叠
摘要
Abstract
Aim:To detect 14 Y-STR loci haplotype genetic polymorphism and investigate its application value on legal physical evidence. Methods: PCR, polyacrylamide gel and silver staining banding techniques were used to detect the distribution of 14 Y-STR loci including DYS713, DYS720, DYS635, DYS456, DYS389 Ⅰ , DYS390, DYS389 Ⅱ, H4, DYS460( A7. 1 ),DYS391, DYS448, DYS393 ,DYS439, DYS392 in 203 unrelated individuals of Han nationality from Henan, and the result was used in 2 cases of forensic evidence. Results: A total of 203 haplotypes were detected in 203 samples, haplotype diversity value was up to 1, and individual recognition rate was 0. 999 976. Used in 2 cases of forensic evidence, accurate judgement was got. Conclusion:The 14 Y-STR loci system has high haplotype diversity and discriminating power.关键词
Y-STR/单倍型/遗传多态性/河南/汉族Key words
Y-STR/haplotype/genetic polymorphism/Henan province/Han population分类
医药卫生引用本文复制引用
杨洪毅,徐朝阳,宋丽君,肖海,李晓文..河南汉族14个Y-STR基因位点单倍型的遗传多态性[J].郑州大学学报（医学版）,2012,47(2):223-225,3.
