郑州大学学报（医学版）2012，Vol.47Issue(2)：232-234,3.DOI:10.3969/j.issn.1671-6825.2012.02.028
卵母细胞第一极体形态与卵胞浆内单精子显微注射受精率和胚胎质量的关系
Relationship between the first polar body morphology of human oocytes and the outcome with intracytoplasmic sperm injection
郝大勇 1张展 1管一春 1王兴玲 1孙丽君 1娄华1
作者信息
- 1. 郑州大学第三附属医院生殖医学中心,郑州,450052
- 折叠
摘要
Abstract
Aim:To understand the relationship between the first polar body morphology of human oocytes and fertilization rate, cleavage rate,and embryo quality after intracytoplasmic sperm injection( ICSI ). Methods:A total of 1 017 human oocytes during 110 treatment cycles with ICSI were selected in human reproductive center. According to the Ebner classification methods, oocytes first polar body were allocated into four types. The 1 017 oocytes were allocated into 3 groups according to the sperm retrieval ways: masturbation sperm retrieval, PESA/TESA sperm retrieval, and frozen semen during ICSI. Relationship between the first polar body morphology of human oocytes and fertilization rate, cleavage rate, and high quality embryo rate were analyzed. Results:Masturbation sperm retrieval patients:the normal fertilization rate and the cleavage rate among 4 groups had obvious difference(P < 0.05 ), The normal fertilization in Ⅰ and Ⅱ polar body morphology of oocytes were higher than that in Ⅲ and Ⅳ polar body morphology, and the clearage rate in I polar body morphology was lower than that in Ⅱ or Ⅲ polar body. PESA/TESA sperm retrieval patients: the normal fertilization rate and high quality embryo rate after 3 days among Ⅰ, Ⅱ , Ⅲ polar body morphology of oocytes had obvious differences(x2 = 8.488 and 6. 789 , P = 0. 044 and 0.034 ), the normal fertilization rate was lower in Ⅰ polar body morphology than that in Ⅱ > Ⅲ polar body morphology and the high quality embryo rate after 3 days was higher in Ⅰ polar body morphology than that in Ⅱ polar body morphology. Conclusion: Normal fertilization may relate with morphology of the first polar body of human oocytes.关键词
卵母细胞/卵胞浆内单精子显微注射/第一极体/胚胎Key words
oocyte/intracytoplasmic sperm injection/the first polar body/embryo分类
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郝大勇,张展,管一春,王兴玲,孙丽君,娄华..卵母细胞第一极体形态与卵胞浆内单精子显微注射受精率和胚胎质量的关系[J].郑州大学学报（医学版）,2012,47(2):232-234,3.
