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人参皂苷Rg3抗肝癌作用机制的研究进展

华琼 华海清

中医学报2012,Vol.27Issue(3):266-269,4.
中医学报2012,Vol.27Issue(3):266-269,4.

人参皂苷Rg3抗肝癌作用机制的研究进展

Research Progress on Anti - hepatoma Mechanisms of Ginsenoside Rg3

华琼 1华海清2

作者信息

  • 1. 南京中医药大学第一临床医学院,江苏南京210046
  • 2. 中国人民解放军第八一医院全军肿瘤中心内科,江苏南京210002
  • 折叠

摘要

Abstract

Objective: To investigate the condition of ginsenoside Rg3 in anti - hepatoma mechanisms. Methods: To collect and analyze the published data of ginsenoside Rg3 on the study of anti - hepatoma mechanisms. Results: Cinsenoside Rg3 is a metamer which is extracted from the traditional chinese herb ginseng. It can induce the apoptosis of liver cancer cells, inhibit the proliferation, invasion, metastasis and formation of new blood vessels,reverse the multidrug resistance of liver cancer cells. Further more,the combination of Rg3 and chemotherapeutic agents can reduce the toxicity and increase therapeutic effects. Conclusion: Cinsenoside Rg3 has anti - hepatoma effects,but the main effect pathways and related targets are not yet clear. It needs to be further researched and explored.

关键词

人参皂苷Rg3/原发性肝癌/肝细胞癌/抗癌作用机制

Key words

Ginsenoside Rg3/primary hepatic carcinoma/hepatic cellular cancer/anti -hepatoma mechanism of action

分类

医药卫生

引用本文复制引用

华琼,华海清..人参皂苷Rg3抗肝癌作用机制的研究进展[J].中医学报,2012,27(3):266-269,4.

基金项目

军区医学科技创新重点课题项目(编号:09Z012) (编号:09Z012)

中医学报

OACSTPCD

1674-8999

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