中医学报2012，Vol.27Issue(3)：322-324,3.
复方土牛膝合剂对急性炎症大鼠MDA、SOD、NO及免疫功能影响的研究
The Effect of Achyranthes Aspera Mixture on MDA,SOD,NO and the Immune Function of Acute Inflammation in Rats
摘要
Abstract
Objective:To observe the effect of Achyranthes aspera mixture on MDA,SOD,NO and the Immune function of acute inflammation in rats. Methods;The aged model was induced by Xylene and the rats were divided into five groups,normal control group,aged model group and Achyranthes aspera mixture in the treatment of aged model group(dose of 0.182 g ? Kg-1 ,0.363 g ? Kg-1 、0.726 g ? Kg－1 ). Results:Compared with the normal group and the corresponding control group,Achyranthes aspera mixture reduces the concentration of MDA,TNF-α and IL-1β activity,increases SOD and NO activity and the number of peripheral white blood cell in aged rats and that promotes T lymphocyte proliferation and enhances NK cell activity(P<0.05). Conclusion; Achyranthes aspera mixture has a certain effect of anti - inflammatory and immune function.关键词
复方土牛膝合剂/急性炎症大鼠/丙二醛/超氧化物歧化酶/一氧化氮/自然杀伤细胞/降低肿瘤坏死因子-α/白细胞介素-1βKey words
achyranthes aspera mixture/acute Inflammation in rats/MDA/SOD/NO/NK/TNF/IL- 1β分类
医药卫生引用本文复制引用
邓敏贞,秦劭晨,黎同明..复方土牛膝合剂对急性炎症大鼠MDA、SOD、NO及免疫功能影响的研究[J].中医学报,2012,27(3):322-324,3.基金项目
广东省自然科学基金项目(编号:K2100027) （编号:K2100027）
