化工进展2012，Vol.31Issue(1)：35-40,6.
微生物法生产1,3-丙二醇不同分离工艺的生产成本分析
Cost analysis on three separation processes in microbial production of 1,3-propanediol
王继艳 1滕虎 1修志龙1
作者信息
- 1. 大连理工大学生命科学与技术学院,辽宁大连116024
- 折叠
摘要
Abstract
The preliminary design for the bioconversion of 1,3-propanediol from glycerol with annual production capacity of 1000 tons was achieved by three separation processes operated sequentially,which were an aqueous two-phase extraction,an alcohol precipitation and an electrodialysis.The process simulation software,ProⅡ,was used to simulate the three downstream processes.Based on energy and material balance,the raw material,utilities and equipments costs of these three processes were calculated.The cost analysis indicated that the total costs of alcohol precipitation,aqueous two-phase extraction and electrodialysis were 14793,14201 and 14345（RMB/t）,respectively.The economic sensitivity analysis showed that the price of glycerol was the key factor influencing the unit costs.The increasing of the concentration and yield of 1,3-propanediol will help to reduce production costs and improve process economic efficiency.关键词
1,3-丙二醇/分离工艺/流程模拟/生产成本/敏感性分析Key words
1/3-propanediol/separation processes/process simulation/production cost/sensitivity analysis分类
生物科学引用本文复制引用
王继艳,滕虎,修志龙..微生物法生产1,3-丙二醇不同分离工艺的生产成本分析[J].化工进展,2012,31(1):35-40,6.
