哈尔滨商业大学学报（自然科学版）2011，Vol.27Issue(5)：662-666,5.
抗风湿涂膜剂的制剂研究
Preparation research of fights rheumatism paints
王建明 1王政超1
作者信息
- 1. 黑龙江中医药大学中医药研究院,哈尔滨150040
- 折叠
摘要
Abstract
To research that the azone and propylene glycol at different concentrations on promoting penetration effects of capsaicin and the total alkaloids in radix aconite and the matrix of choice about paints . Using modified Franz diffusion cells, determination of contents of capsaicin were assayed by HPLC, determination of contents of the total alkaloids in Radix Aconiti were assayed by acid dyeing colorimetry. The contrast between azone and the propylene glycol at different contents with capsaicin or the total alkaloids in Radix Aconiti on promoting percutaneous absorption. According the transparency, viscosity and into the membranous to determine addition amount about the matrix - shell of oligo. There were significant differences between azone and propylene glycol at different contents with capsaicin, but it was not obvious with the total alkaloids in Radix Aconiti. The effect of 1% (V/V) azone and 6% ( V/V) propylene glycol on promoting percutaneous absorption of capsaicin and the total alkaloids in Radix Aconiti was the best. The best effect was matrix - shell of oligo that add 10 times the composition medicine dose.关键词
辣椒素/川乌总生物碱/透皮吸收/制备工艺Key words
capsaicin/ total alkaloids in Radix Aconiti/ percutaneous absorption/ manufacture process分类
医药卫生引用本文复制引用
王建明,王政超..抗风湿涂膜剂的制剂研究[J].哈尔滨商业大学学报（自然科学版）,2011,27(5):662-666,5.
