湖南中医药大学学报2012，Vol.32Issue(1)：67-69,78,4.DOI:10.3969/j.issn.1674-070X.2012.01.020.067.03
电针对大鼠脑出血后脑血肿的影响
Effects of electroacupuncture treatment on cerebral hematoma after intracerebral hemorrhage in rats
摘要
Abstract
Objective To investigate the therapeutic effect of electroacupuncture treatment on the early stage of cerebral hematoma formation following after intracerebral hemorrhage(ICH)in rats. Methods Ten animals were randomly selected as sham operation group(SOG)from 60 Wistar rats and the remaining rats were used to prepare the model of cerebral hematoma after ICH. Then, 30 modeled rats were randomly divided into 3 groups, I.e. Model group(MG), extra-meridiansacupoints group(EMG)and electro-acupoint group(EAG), 10 rats per group. Acupoints Renzhong(DU26)and Fengfu(DU26)were used in EAG and the extra-point in hips of rats in EMG; elctro-puncturing 20 mins, once 24 hours, and lasting 3 days; and the electro-puncturing were used not in SOG and MG. Results Except for SOG, the various size of bleeding spots and hematomas were within cerebral issue; under the microscopic observation, the different degrees of cerebral edema around the hematoma, swelling nerve cells, nucleus fragmentation dissolve or disappear, red blood cells visible within the organization were seen in rat brain tissue within the injection area and there existed different degrees of inflammatory cell infiltration; compared with EMG and MG, hematoma diameter were significantly reduced in EAG(P<0.05). Conclusion Early acupuncture intervention can significantly reduce the size of hematoma and effectively control the occurrence and development of cerebral hematoma following ICH.关键词
电针/脑出血/脑血肿/大鼠Key words
electroacupuncture/intracerebral hemorrhage/cerebral hematoma/rats分类
医药卫生引用本文复制引用
曹健,吴生兵,周美启,高纺,杨影..电针对大鼠脑出血后脑血肿的影响[J].湖南中医药大学学报,2012,32(1):67-69,78,4.基金项目
安徽中医学院自然科学基金资助项目(2010zr017B). （2010zr017B）
