摘要
Abstract
Objective To find out the effects of Peony Root and Ramulus Cinnamomi on anti-inflammatory when used separately and in combina- tion.Methods 100 Kunming mice.male and female,were randomly divided into five groups, Including the control group,carrageenan group, white peony group, Gui Zhi group, compatibility group. 30 minutes after administration, carrageenan pleurisy in mice modeling. 5 hours of modeling, eye blood, detection of malondialdehyde, elastase content and the effect on CAMP-PDE activity.Results Compared with the control group, carrageenan MDA and elastase were significantly higher, P＜0.05. And carrageenan group, white peony root group and Guizhi group,inhibited the increase of MDA and elastase levels, P＜0.05; White peony root and cassia twig of compatibility group, obviously inhibited the increase of MDA and elastase levels, P＜0.01. Compared with carrageenan group, white peony root group、Guizhi group obviously reduced CAMP-PDE activity(P＜0.05).Compared with carrageenan group, the compatibility group obviously reduced CAMP-PDE activity(P＜0.01).ConcIusion The drugs combination is more effective on anti-inflammatory.关键词
白芍/桂枝/配伍/药理Key words
Peony root/Ramulus cinnamomi/Combination/Pharmacological分类
医药卫生
