华西口腔医学杂志2012，Vol.30Issue(1)：22-24,3.DOI:10.3969/j.issn.1000-1182.2012.01.005
赤藓糖醇对变异链球菌作用机制的实验研究
Study on the mechanism of erythritol effecting on Streptococcus mutans
摘要
Abstract
Objective To evaluate the effect of erythritol on cell wall structure of Streptococcus mutans (S.mutans) and explore its potential mechanism. Methods Enzyme activities of lactate dehydrogenase (LDH) in bacterial solution were detected under respective condition of sucrose and erythritol. A scanning electron microscope (SEM) was used to investigate the change of Smutans' cell wall under the condition of sucrose and erythritol. Results Enzyme activities of LDH in erythritol culture medium were different from that in sucrose, but the difference was slight. SEM observation showed the integrity of cell wall was not destroyed and no content leaked out. Conclusion It's suggested that erythritol has an antibacterial effect on Smutans through no affecting on the normal structure of the cell wall of S.mutans.关键词
赤藓糖醇/变异链球菌/乳酸脱氢酶/扫描电镜Key words
erythritol/ Streptococcus mutans/ lactate dehydrogenase/ scanning electron microscope分类
医药卫生引用本文复制引用
姚军,张佳丽..赤藓糖醇对变异链球菌作用机制的实验研究[J].华西口腔医学杂志,2012,30(1):22-24,3.基金项目
福建省青年人才创新基金资助项目(2007F3033) （2007F3033）
