四川大学学报（医学版）2012，Vol.43Issue(1)：86-90,5.
原发性肾平滑肌肉瘤13例临床病理分析
Primary Leiomyosarcoma of the Kidney: a Clinicopathological Study of 13 Cases at a High-volume Institution
熊子兵 1石明 1Kunwar Ashok 1陈铌 2张朋 1曾浩 1李响1
作者信息
- 1. 四川大学华西医院泌尿外科,成都 610041
- 2. 四川大学华西医院 病理研究室,成都 610041
- 折叠
摘要
Abstract
Objective To analyze the clinical characteristics, treatment, and survival of adult patients with renal leiomyosarcoma treated at our institution during the past 13 years. Methods A retrospective review was performed to collect the demographic distribution, clinical manifestation, treatment, and outcome data about 13 adult patients of renal leiomyosarcoma treated at our institution from January 1996 to January 2008. The clinical parameters were analyzed to determine the effects on survival by logistic regression. Results Mean age at diagnosis was 45. 7 years (range 20 to 71) , and 61. 5% (8/13) were female. Mean tumor diameter was (11. 1 ± 10. 2) cm (range 3 to 34 cm), 53. 9% (7/13) had direct invasion of renal capsule, and 23. 1% (3/13) had lymphovascular invasion. The follow-up information of 11 cases was available, and duration of follow-up was an average of 39. 2 (range 9-81) months. The overall survival (OS) rate at 1, 3, and 5 years was 81. 8%, 54. 5%, and 16. 2% respectively. 8 (72.7%) patients developed metastasis, and 9 (81. 8%) patients eventually died. The survival of the patients did not show correlations with age, pathologic grade, extrarenal component, lymphovascular invasion, complete resection or not and chemotherapy or not. Conclusion Primary renal leiomyosarcoma has a poor survival prognosis regardless of the underlying histological and clinical features.关键词
肾脏恶性肿瘤/平滑肌肉瘤/生存/预后Key words
Leiomyosarcoma/Kidney/Survival/Prognosis引用本文复制引用
熊子兵,石明,Kunwar Ashok,陈铌,张朋,曾浩,李响..原发性肾平滑肌肉瘤13例临床病理分析[J].四川大学学报（医学版）,2012,43(1):86-90,5.
