解放军医学杂志2012，Vol.37Issue(1)：17-19,3.
复方氨基酸胶囊对舰艇官兵免疫功能的影响
Effects of compound amino acids capsule on the immunological function of naval servicemen
摘要
Abstract
Objective The present study was to investigate the effects of the compound amino acids capsule on the immunological function of the naval servicemen during military activity. Methods The subjects included 100 officers and soldiers, whose Modified Fatigue Rating Scale (MFIS) scores were >21 points. The participants were randomly divided into two groups, namely, the amino acids capsule group and placebo group (n=50). Under the condition of military operations, either amino acid or placebo capsules was given for 14 days continuously. The humoral immune indices, I.e., IgG, IgA, IgM, and complements C3 and C4, were measured with immunoturbidimetry. The percentage of peripheral blood CD subsets was measured using flow cytometry on the first day and 14th day. Results The levels of IgG, IgM, and complement C3 of the capsule group were significantly higher in 14th day than that on the first day (P<0.05), and no significant difference of their levels was observed in the control group. The CD3+CD4+T lymphocytes and CD3-CD19+ B lymphocytes in the capsule group on the 14th day were higher than that on the first day, whereas the CD3-CD56+ NK lymphocytes decreased significantly (P<0.0S). There was no significant difference in the control group. Conclusion Compound amino acids capsule can improve the humoral and cellular immunological function of naval servicemen.关键词
军事人员/氨基酸类/疲劳/免疫Key words
military personnel/ amino acids/ fatigue/ immunity分类
医药卫生引用本文复制引用
钟海忠,肖立宁,陈来园,高朝辉,王仁安,黄文,李兆申..复方氨基酸胶囊对舰艇官兵免疫功能的影响[J].解放军医学杂志,2012,37(1):17-19,3.基金项目
全军"十一五"医药卫生科研基金重点课题(08Z022) （08Z022）
2010年深圳南山科技研发重点课题(2010-52) （2010-52）
