解放军医学杂志2012，Vol.37Issue(2)：94-97,4.
六个miniSTR基因座在中国汉族人群的复合扩增研究
Further characterization of six miniSTR loci in the Han population from China
摘要
Abstract
Objective To describe the characterization of two miniplex further:NC01 (D10S1248,D14S1434 and D22S1045),which was recommended by EDNAP/ENFSI,and a new miniplex one (D2S2944,D18S872 and D19S591).Methods DNA was extracted using the Chelex-100 extraction method.The products were genotyped by ABI PRISM(☉) 310 Genetic Analyzer and the results were analyzed with GeneScan 3.7 and GenoTyper 3.7 software.Results All loci meet Hardy-Weinberg equilibrium.The combined power of discrimination for the six loci in Chinese population was 0.9999 and the cumulative probability of exclusion was 0.9793.We also compared the sequencing data of NC01 with other different ethic groups.Conclusion Two miniplex were constructed.These miniSTR makers have different characterization in different ethic groups.关键词
法医遗传学/微小片段短串联重复序列/基因扩增/降解DNAKey words
forensic genetics/ mini short tandem repeat (miniSTR)/ gene amplification/ degraded DNA分类
医药卫生引用本文复制引用
贾振军,石美森,蒋师,武尉,李英碧,吴谨,侯一平..六个miniSTR基因座在中国汉族人群的复合扩增研究[J].解放军医学杂志,2012,37(2):94-97,4.基金项目
This work was supported by the National Natural Science Foundation for Young Scientists of China (30801320),and the Program for New Century Excellent Talents in University (NCET-10-0773),and the New-Star Program of Science and Technology of Beijing Metropolis (2010B073) （30801320）
