摘要
Abstract
Objective：To explore the influencing factors of the prognosis of hepatic enecphal-opathy（HE）.Methods： 90 cases of hepatic encephalopathy which had been treated in affiliated hospital of Jianghan university were selected,with a strict adoption standard which excluded all kinds of diseases probably leading to coma and behavior disorder.Clinical and laboratory parameters（prothrombin activity,serum albumin,glutamyl transpeptidase,serum sodium,serum bilirubin,Child-Pugh classification,upper gastrointestinal bleeding,ascites,primary liver cancer,hepatorenal syndrome,secondary infection）were investigated.The above factors and their relationship with prognosis（within 30 days of survival and death） were researched.The samples were compared using chi-square test,P 0.05 had statistical significance.Results： The mortality within 30 days of patients with high serum bilirubin（ 51.3 mol/L）,low prothrombin activity（ 30%）,low serum albumin（28 g/L）,low blood sodium（ 135 mmol/L）,Child-Pugh grade C and ac-companied with ascites,upper gastrointestinal bleeding,hepatorenal syndrome,infection was sig-nificantly increased,comparing with the other patients.The difference was statistically significant（P 0.05）.The influence of blood transpeptidase level on the mortality within 30 days of patients was not significant（P 0.05）,as well as accompanying with primary liver cancer or not.Conclusion： Multiple factors can influence the prognosis of hepatic encephalopathy.Timely diagnosis and proper treatment can save lives of the patients,and improve the prognosis of the patients.关键词
肝性脑病/预后/病理生理学Key words
hepatic encephalopathy/prognosis/pathological physiology分类
医药卫生
