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血清应答因子、平滑肌肌动蛋白在食管鳞癌中表达及意义

何喜 薛忠文 徐洪 王士杰

解剖学杂志2011,Vol.34Issue(6):755-757,3.
解剖学杂志2011,Vol.34Issue(6):755-757,3.

血清应答因子、平滑肌肌动蛋白在食管鳞癌中表达及意义

Clinical significance of serum response factor and α-smooth muscle actin expression in esophageal carcinoma

何喜 1薛忠文 1徐洪 1王士杰1

作者信息

  • 1. 河北医科大学外科学教研室,石家庄050011
  • 折叠

摘要

Abstract

Objective-. To explore the expression and clinical significance of serum response factor (SRF) and α-smooth muscle actin (α-SMA) in esophageal carcinoma. Methods-. Immunohistochemical staining for SRF and crSMA was performed to test biopsy specimens of human esophageal carcinoma tissues, including esophageal carcinoma (73 cases) and normal esophageal tissues (30 cases). Results-. Immunohistochemical study showed that SRF and α-SMA protein expression in esophageal carcinoma was higher than that in normal esophageal tissues, and was significantly relevant with the differentiation degree, depth of invasion and lymph node metastasis. Conclusion: SRF and α-SMA high-expression in esophageal carcinoma is associated with invasion and matastasis, which is a potential target of esophageal carcinoma treatment.

关键词

食管鳞癌/血清应答因子/平滑肌肌动蛋白

Key words

esophageal carcinoma/serum response factor/α-smooth muscle actin

引用本文复制引用

何喜,薛忠文,徐洪,王士杰..血清应答因子、平滑肌肌动蛋白在食管鳞癌中表达及意义[J].解剖学杂志,2011,34(6):755-757,3.

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