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桡动脉痉挛血管扩张剂干预研究

李小龙 李芳 董鹏 靳维华 曲涛 王斌

实用临床医药杂志2011,Vol.15Issue(19):26-28,3.
实用临床医药杂志2011,Vol.15Issue(19):26-28,3.

桡动脉痉挛血管扩张剂干预研究

The study of radial artery spasm vasodilator intervention

李小龙 1李芳 2董鹏 2靳维华 2曲涛 2王斌2

作者信息

  • 1. 江苏省常州市中医医院心内科,江苏常州,213003
  • 2. 北京大学航天临床医学院心脏中心,北京,100049
  • 折叠

摘要

Abstract

Objective To explore the effect of different vasodilators on radial artery spasm (RAS) by radial artery angiography. Methods 180 patients undergoing transradial coronary an-giography or angioplasty were randomly divided into three groups: group A (nitroglycerin 200 jug), group B (Nicardipine 200 /ng) and group C (100 jug of Nicardipine plus 100 fig of nitroglycerin) with 60 patients in each group. The radial arteriography was performed through the sheath at baseline, 1 min and 2 min after injection spasmolytic regimen to relieve vasospasms. The diameter of radial artery spasmsegment and the segment of normal reference were compared at baseline, 1 min and 2 min after injection of spasmolytic regimen in 3 groups. Results For the diameter of normal reference segment of radial artery , there were significant difference among baseline, 1 min and 2 min after injection spasmolytic regimen (P<0.05) in group A and B group. There were significant difference between baseline and 1 min after injection spasmolytic regimen (F<0.05), but no significant difference between 1 min and 2 min after injection spasmolytic regimen in group C (P>0.05). For the diameter of spasm segment, there were significant difference among baseline, 1 min and 2 min after injection in each group (P<0.05). There were significant difference 2 min after injection between previous two groups and group B (P<0.05). Conclusion The radial artery can be expanded by nitroglycerin and Nicardipine significantly, but there are greater advantage by two combination.

关键词

桡动脉/痉挛/硝酸甘油/尼卡地平

Key words

radial artery/ spasm/ nitroglycerin/ Nicardipine

分类

医药卫生

引用本文复制引用

李小龙,李芳,董鹏,靳维华,曲涛,王斌..桡动脉痉挛血管扩张剂干预研究[J].实用临床医药杂志,2011,15(19):26-28,3.

基金项目

中国高校医学期刊临床专项资金资助项目(11120023) (11120023)

实用临床医药杂志

OACSTPCD

1672-2353

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