实用临床医药杂志2011,Vol.15Issue(19):26-28,3.
桡动脉痉挛血管扩张剂干预研究
The study of radial artery spasm vasodilator intervention
摘要
Abstract
Objective To explore the effect of different vasodilators on radial artery spasm (RAS) by radial artery angiography. Methods 180 patients undergoing transradial coronary an-giography or angioplasty were randomly divided into three groups: group A (nitroglycerin 200 jug), group B (Nicardipine 200 /ng) and group C (100 jug of Nicardipine plus 100 fig of nitroglycerin) with 60 patients in each group. The radial arteriography was performed through the sheath at baseline, 1 min and 2 min after injection spasmolytic regimen to relieve vasospasms. The diameter of radial artery spasmsegment and the segment of normal reference were compared at baseline, 1 min and 2 min after injection of spasmolytic regimen in 3 groups. Results For the diameter of normal reference segment of radial artery , there were significant difference among baseline, 1 min and 2 min after injection spasmolytic regimen (P<0.05) in group A and B group. There were significant difference between baseline and 1 min after injection spasmolytic regimen (F<0.05), but no significant difference between 1 min and 2 min after injection spasmolytic regimen in group C (P>0.05). For the diameter of spasm segment, there were significant difference among baseline, 1 min and 2 min after injection in each group (P<0.05). There were significant difference 2 min after injection between previous two groups and group B (P<0.05). Conclusion The radial artery can be expanded by nitroglycerin and Nicardipine significantly, but there are greater advantage by two combination.关键词
桡动脉/痉挛/硝酸甘油/尼卡地平Key words
radial artery/ spasm/ nitroglycerin/ Nicardipine分类
医药卫生引用本文复制引用
李小龙,李芳,董鹏,靳维华,曲涛,王斌..桡动脉痉挛血管扩张剂干预研究[J].实用临床医药杂志,2011,15(19):26-28,3.基金项目
中国高校医学期刊临床专项资金资助项目(11120023) (11120023)