实用临床医药杂志2011，Vol.15Issue(20)：81-83,3.
全髋关节置换围术期应用塞来昔布超前镇痛的疗效评估
The effect of Celecoxib preemptive analgesia on total hip replacement
阮小燕1
作者信息
- 1. 扬州大学临床医学院骨科,江苏扬州,225001
- 折叠
摘要
Abstract
Objective To investigate Celecoxib's preemptive analgesia effect on total hip re-placement(THR), and to find whether it has the effect of reducing the dosage and side effects of anaesthetic drugs. Methods Forty THR patients were randomly divided into two groups with equal members. The preoperative analgesia group (Celecoxib oral 400 mg preoperative, 200 mg 6 h after operation, the after 2 days 200 mg oral Bid) and the contrast group (No Celecoxib used before operation) . PECA were used 48 h postoperatively on all the patients of the 2 groups. VAS was recorded during perioperative period. The dosage and side effects of anaesthetic drugs were also observed. Results Celecoxib can reduce the VAS of THR, and reduce the use of other anaesthetic drugs and . Side effects (P < 0.05). Conclusion The use of Celecoxib in the perioperative period can alleviate pains after surgery and reduce the intake of anaesthetic drugs with less side effects. It is very important to help hip replacement patients to have early functional exercise. Thus it helps the functional recovery.关键词
塞来昔布/超前镇痛/全髋关节置换Key words
Celecoxib/ preemptive analgesia/ total hip replacement分类
医药卫生引用本文复制引用
阮小燕..全髋关节置换围术期应用塞来昔布超前镇痛的疗效评估[J].实用临床医药杂志,2011,15(20):81-83,3.
