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非ST段抬高型急性冠状动脉综合征患者应用国产替罗非班的疗效观察

赵伟 庞志华

实用临床医药杂志2012,Vol.16Issue(1):42-44,3.
实用临床医药杂志2012,Vol.16Issue(1):42-44,3.

非ST段抬高型急性冠状动脉综合征患者应用国产替罗非班的疗效观察

Clinical study of domestic tirofiban in patients with non- ST- segment elevation acute coronary syndrome (NSTE - ACS)

赵伟 1庞志华2

作者信息

  • 1. 天津市红桥区丁字沽街社区服务中心,天津,300400
  • 2. 天津市天和医院心内科,天津,300050
  • 折叠

摘要

Abstract

Objective To evaluate the effect and safety of domestic tirofiban in NSTE -ACS patients. Methods One hundred and fifty NSTE - ACS patients who refused the treatment of PCI treatment were divided into tirofiban group and control group (conventional, therapy). The events of recurrent angina, myocardial infarction and cardiogenic sudden death, mucocutaneous bleeding and the changes of BNP, cTnT, platelet inhibition rate level before and after .treatment were observed. Results Compared with the control group, tirofiban group had a significant lower 48 h end event rate. There was no significant difference in bleeding complications between the two groups. The level of cTnT and BNP were significantly decreased after treatment, and the effect of the tirofiban group was better than that of the control group. Platelet aggregation rate in tirofiban group was significantly higher than that of the control group. Conclusion Domestic tirofiban has good effect and tolerance for patients with NSTE - ACS, meanwhile it does not increase hemorrhage risk.

关键词

替罗非班/非ST段抬高/急性冠状动脉综合征

Key words

tirofiban/ non - ST - segment elevation acute coronary syndrome (NSTE-ACS)/ acute coronary syndrome

分类

医药卫生

引用本文复制引用

赵伟,庞志华..非ST段抬高型急性冠状动脉综合征患者应用国产替罗非班的疗效观察[J].实用临床医药杂志,2012,16(1):42-44,3.

实用临床医药杂志

OACSTPCD

1672-2353

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