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吉西他滨联合化疗在晚期胰腺癌治疗中的作用探讨

刘一宏 崔蕊

实用临床医药杂志2012,Vol.16Issue(1):85-86,2.
实用临床医药杂志2012,Vol.16Issue(1):85-86,2.

吉西他滨联合化疗在晚期胰腺癌治疗中的作用探讨

Gemcitabine- based chemotherapy for advanced pancreatic cancer

刘一宏 1崔蕊1

作者信息

  • 1. 陕西省榆林市第一医院药剂科,陕西榆林,719000
  • 折叠

摘要

Abstract

Objective To explore the clinical effect of gemcitabine - based chemotherapy on advanced pancreatic cancer. Methods Fifty patients with locally advanced pancreatic cancer were randomized equally into combined chemotherapy group and control group. The control group received gemcitabine monotherapy, while the combined chemotherapy group received gemcitabine combined with cisplatin or oxaliplatin. Objective responses, clinical benefit responses and toxicity responses of the two groups were observed. Results The disease control rate of the combined chemotherapy group was significantly higher than that of the control group. The toxicity rate of the combined chemotherapy group was slightly higher than that of the control group. Conclusion Gemcitabine - based chemotherapy program for advanced pancreatic cancer has similar clinical efficacy compared with' gemcitabine monotherapy.

关键词

吉西他滨/晚期/胰腺癌

Key words

gemcitabine/ advanced/ pancreatic cancer

分类

医药卫生

引用本文复制引用

刘一宏,崔蕊..吉西他滨联合化疗在晚期胰腺癌治疗中的作用探讨[J].实用临床医药杂志,2012,16(1):85-86,2.

基金项目

中国高校科技期刊临床专项资金(11220004) (11220004)

实用临床医药杂志

OACSTPCD

1672-2353

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