军医进修学院学报2011，Vol.32Issue(12)：1217-1219,3.DOI:11-3275/R.20110704.0903.001
累及气道的复发性多软骨炎20例临床分析
Recurrent polychondritis involving airway:Clinical Analysis of 20 patients
薛新颖 1王娜 1薛庆亮 1张丽娜 1郭丽娜 1汪建新1
作者信息
摘要
Abstract
Objective To study the diagnostic and therapeutic methods of recurrent polychondritis(RP) involving airway. Methods Clinical data about 20 patients with RP involving airway admitted to our hospital from 1998 to 2010 were retrospectively analyzed. Results The airway was involved in 20 RP patients, accounting for 45.45%(20/44). Of the 20 patients, 10 were males and 10 were females with a mean age of 42.25 years(range 20-72 years). The main clinical manifestations were cough, expectoration, chest tightness, shortness of breath, hoarseness and dyspnea. Abnormal chest CT findings included local and diffuse airway wall thickening, airway stenosis and airway wall calcification. Airway collapse, severe airway stenosis, pulmonary infection and atelectasis were usually found in severe patients. Abnormal bronchoscopy showed mucomembranous hyperemia, edema, thickening and unclear cartilaginous ring. Disappeared cartilaginous ring, airway collapse and obvious airway stenosis were identified in severe patients. Therapeutic agents used were corticosteroids, anti-inflammatory drugs, immunosuppressive agents, etc. After treatment, 18(90%) patients recovered and 2 died. Conclusion RP involving airway has a variety of clinical manifestations and is easy to be misdiagnosed. The diagnosis of RP mainly depends on its clinical manifestations, chest CT findings, bronchoscopic findings and lung function tests. Early use of corticosteroids can significantly improve its clinical symptoms and prognosis.关键词
多软骨炎,复发性/气道阻塞/诊断/治疗Key words
polychondritis, relapsing/airway obstruction/diagnosis/therapy分类
医药卫生引用本文复制引用
薛新颖,王娜,薛庆亮,张丽娜,郭丽娜,汪建新..累及气道的复发性多软骨炎20例临床分析[J].军医进修学院学报,2011,32(12):1217-1219,3.
