军医进修学院学报2012,Vol.33Issue(2):151-152,164,3.DOI:11-3275/R.20110714.1650.001
肺泡蛋白沉着症9例临床分析
Pulmonary alveolar proteinosis:A clinical analysis of 9 cases
张曙 1磨国鑫 1管希周 1胡红 1陈良安1
作者信息
- 1. 解放军总医院 呼吸科,北京 100853
- 折叠
摘要
Abstract
Objective To study the clinical features, therapeutic effect, and prognosis of pulmonary alveolar proteinosis(PAP). Methods Clinical data about 9 cases of PAP(4 males and 5 females) were retrospectively analyzed with its related literature reviewed. Results The onset age of PAP was 42 years(mean 29-65 years). The main clinical manifestations included dyspea in 6 cases, cough in 4 cases, expectoration in 2 cases, and fever in 1 case. No symptom was observed in 2 cases. Chest X-ray showed different lesions and high resolution computerized tomography (HRCT) revealed geographic and "crazy-paving" lesions throughout both lungs. Diagnosis of PAP was established by radio-assisted transbronchoscopic lung biopsy(TBLB) and bronchoalveolar lavage fluid(BALF). Conclusion PAP is mainly characterized by dyspea and cough, geographic and "crazy-paving" lesions throughout both lungs found in HRCT, and is diagnosed based on the findings in TBLB or BALK Large volume lavage of the whole lung is an effective and safe therapeutic procedure for it.关键词
肺泡蛋白沉着症/肺疾病/诊断/治疗Key words
pulmonary alveolar proteinosis/ lung diseases/ diagnosis/ therapy分类
医药卫生引用本文复制引用
张曙,磨国鑫,管希周,胡红,陈良安..肺泡蛋白沉着症9例临床分析[J].军医进修学院学报,2012,33(2):151-152,164,3.