昆明医学院学报2011，Vol.32Issue(10)：120-123,4.
宫颈癌组织中Ki-67及Survivin的表达及其相关性研究
Clinical Research of the Expression and Correlation of KI-67 and Survivin in Cervical Carcinoma
李淼 1李力 1陶丽 1钱智1
作者信息
- 1. 保定市第一中心医院,河北保定 071000
- 折叠
摘要
Abstract
Objective To study the relationship between the expression of KI-67and Survivin in cervical carcinoma and the clinical feature of cervical carcinoma and to observe the correlation between KI-67 and Survivin in cervical carcinoma. Methods Using streptavidin-biotin peroxidase ( SP) method, we examined the expression of KI-67and Survivin in 73 cases of cervical carcinoma, 25 cases of cervical intraepithelial neoplasia (CIN) and 20 cases of chronic cervicitis. Results The expression of KI-67 and Survivin presented a growing trend from chronic cervicitis to cervical carcinoma. The expression of KI-67 and Survivin were related to the clinical stages of cervical carcinoma. A positive correlation existed between KI-67and Survivin (r = 0.701, P < 0.01). Conclusion The expression of KI-67and Survivin in cervical carcinoma can reflect the local invasion activity and metastasizing proficiency of cervical carcinoma. They are closely related to metastasis, clinical stages and prognosis of cervical carcinoma.关键词
宫颈癌/免疫组织化学/Ki-67/SurvivinKey words
Cervical carcinoma/ Immunohistochemistry/ KI-67/ Survivin分类
医药卫生引用本文复制引用
李淼,李力,陶丽,钱智..宫颈癌组织中Ki-67及Survivin的表达及其相关性研究[J].昆明医学院学报,2011,32(10):120-123,4.
