口腔颌面外科杂志2011，Vol.21Issue(6)：389-393,5.DOI:10.3969/j.issn.1005-4979.2011.06.002
小型猪骨膜成骨修复下颌骨节段性缺损的研究
Periosteal Osteogenesis in Mandibular Reconstruction: a Study in Miniature Pigs
摘要
Abstract
Objective: To clarify the feasibility of periosteal osteogenesis in situ to repair the mandibular segmental defect. Methods: The premolars and molars in the right mandible of eight 13-month old minipigs were extracted. Three months later, the animals were randomly divided into two groups (A and B), four animals in each group. In group A, 30mm and 40mm bone segments were removed from the right mandible, and neighbouring periosteum was preserved. In group B, 30mm and 40mm bone segments were removed from the right mandible, and the periosteum was removed stimultaneonsly. The defects in both groups were retained and further reconstructed by titanium plates. The mandibles reconstruction were checked by X-ray examinations at 4, 8 and 12 weeks after operation. Results: At the end of 12 weeks, the regular new bones were formed in group A, which meant bone repair was finished. Slight irregular new bones formed in group B, which meant bone repair was not finished. Conclusion: Using periosteal in situ osteogenesis can repair the mandibular segmental defect.关键词
骨膜原位成骨/下颌骨缺损/骨修复/猪Key words
periosteal in situ osteogenesis/ mandibular defect/ bone repair/ pig分类
医药卫生引用本文复制引用
杨林春,王飘,陆超,田欢,潘巨利..小型猪骨膜成骨修复下颌骨节段性缺损的研究[J].口腔颌面外科杂志,2011,21(6):389-393,5.基金项目
北京市东城区2011年重点科技项目资助 （）
首都医学发展基金项目(2007-3096) （2007-3096）
