临床骨科杂志2012，Vol.15Issue(1)：102-105,4.
硫酸钙骨水泥强化骨质疏松绵羊腰椎的生物力学研究
Biomechanical study on augmentation of osteoporotic sheep vertebrae with calcium sulfate cement:in vivo study
张军华 1张炼1
作者信息
- 1. 兰州军区兰州总医院脊柱外科,甘肃,兰州,730050
- 折叠
摘要
Abstract
Objective To evaluate biomechanical performance of osteoporotic lumbar vertebral body augmented with calcium sulfate cement ( CSC ) in ovariectomized sheep. Methods Four female adult sheep were treated with bilateral ovariectomy. Bone mineral density ( BMD ) of lumbar vertebrae of all sheep was measured before the treatment and one year after of the treatment. L2 ~ L5 of each sheep and total 16 vertebrae were grouped into CSC and blank group with 8 vertebrae in each group. In CSC group, vertebrae were augmented with CSC( 2. 0 ml ) through transpedicular approach. There was no augmentation in blank group. Each vertebra BMD of L2 ~ L5 in CSC group was measured 12 weeks later. Then all sheep were killed and L2 ~ L5 were prepared for compression test. The ultimate compared stres-ses( (σult )and energy absorption value( EAV )of each group were recorded. Results There was a significant decrease in average BMD of lumbar one year after ovariectomy( P < 0. 05 ). The osteoporotic lumbar vertebral experiment was successful. 12 weeks after augmentation with CSC,BMD,σult and EAV in CSC group were significantly higher than those in blank group( P <0. 05 ). There was a positive linear relationship between BMD and σult as well as between BMD and EAV ( P < 0. 05 ). Conclusions Calcium sulfate cement can significantly increase BMD of osteoporotic vertebrae and enhance biomechanical strength, which will avoid or decrease the risks of osteoporotic vertebral fractures.关键词
硫酸钙骨水泥/骨质疏松/腰椎/最大压缩应力/能量吸收值Key words
calcium sulfate cement/osteoporosis/lumbar vertebrae/ulitimate compressive stress/energy absorption value分类
医药卫生引用本文复制引用
张军华,张炼..硫酸钙骨水泥强化骨质疏松绵羊腰椎的生物力学研究[J].临床骨科杂志,2012,15(1):102-105,4.
