临床口腔医学杂志2011，Vol.27Issue(12)：724-726,3.DOI:10.3969/j.issn.1003-1634.2011.12.007
HAART对HIV感染者唾液d类疱疹病毒5-8型分布的影响
Effects of HAART on the prevalence of cytomegalovirus,herpesviruses 6,7 and 8 in saliva from human im munodeficiency virus-seropositive subjects.
摘要
Abstract
Objective: This study aimed to determine the presence of CMV, HHV-6, HHV-7 and HHV-8 and HHV-8 in the saliva of HIV-seropositive patients with HAART and non-HAART. Method:CMV, HHV-6, HHV-7 and HHV-8 DNA of Unstimulated whole saliva from 245 HIV-infected patients and 30 healthy HIV-seronegative controls were analyzed by nested- PCR assays. The data was analyzed by the use of SPSS Statistical software version 18.0. Result: There was no difference of detection rates of these four HHVs in saliva between HIV patients with HAART group and non-HAART group CP >0.05) .HAART group, non-HAART group compared with the normal group differences,and the three groups are present CMV, HHV-6, HHV-7 and HHV-8 multiple infections. Conclusion:Oral herpesvirus infection in patients with HIV infection is very common, of which the most prominent are HHV-6 and HHV-7. Saliva may play a possible role in HHVs spread.关键词
人类获得性免疫缺陷病毒/高效抗逆转录病毒治疗/人类疱疹病毒/巢式多聚合酶链式反应/唾液Key words
Human Immunodeficiency Virus/ highly active antiretroviral therapy (HAART)/ human herpesvirus (HHV)/nested-PCR/ saliva分类
医药卫生引用本文复制引用
葛柳莹,李承文,白劲松,史会萍,李榕,李重熙,段开文..HAART对HIV感染者唾液d类疱疹病毒5-8型分布的影响[J].临床口腔医学杂志,2011,27(12):724-726,3.基金项目
国家自然科学基金资助项目(30860315,81160135) （30860315,81160135）
云南省应用基础研究资助项目(2008ZC 146M). （2008ZC 146M）
