临床输血与检验2012，Vol.14Issue(1)：40-43,4.DOI:10.3969/j.issn.1671-2587.2012.01.012
检测冷沉淀物中Fg、FⅧ最佳稀释倍数的探讨
The Pilot Study of Dilution Ratio in Tests of Cryoprecipitate
摘要
Abstract
Objective To find the best dilution ratio of cryoprecipitate in quality control tests of fibrinogen(Fg) content and FVIII activity,to guarantee the accuracy of the test results. Methods Cryoprecipitate were prepared according to Standards for whole blood and blood components quality and detected with fully automated blood coagulation analyzer Sys-mex-CA550. The results of different dilution ratio were analyzed by statistics. Results As for Fg test, there was significant difference between the results of original sample and doubling diluted sample(P<0. 01),while no significant difference between doubling and fourfold diluted sampleCPX). 05). As for FVIII test, there was significant difference between the results of fourfold and eightfold diluted sample(P<0. 01) .while for each sample, 2 CV<40%. Conclusion With the available standard curve of Sysmex-CA550, the best dilution ratio was doubling dilution for Fg test, and fourfold dilution for F VI before testing on machine.关键词
冷沉淀/质量控制/凝血因子Ⅷ/纤维蛋白原/稀释倍数Key words
Cryoprecipitate/Quality control/Coagulant factor FVIII/Fibrinogen/Dilution ratio分类
医药卫生引用本文复制引用
魏延民,樊晶,李浩泷..检测冷沉淀物中Fg、FⅧ最佳稀释倍数的探讨[J].临床输血与检验,2012,14(1):40-43,4.
