聊城大学学报：自然科学版2011，Vol.24Issue(3)：29-33,5.
限食程度对KM小鼠体重和能量代谢的影响
Effect of Mild and Sever Food Restriction on Body Mass and Energy Budget in KM Mice
摘要
Abstract
The present study aimed to examine the significance and the role of physiological regulations of body mass and energy budget in small mammals in the adaptation to variations of food availability.Adult male KM mice were stochastically restricted to 75% and 50% of ad libitum food intake for four weeks and then refed ad libitum for another four weeks.Body mass,food intake,basal metabolic rate（BMR） and body composition were measured.Food-restricted mice increased BMR and the weight of gastrointestinal tracts,but decreased body mass,carcass mass,body fat content compared with controls.After 4 weeks of refeeding,BMR and body mass recovered to the levels of controls,whereas body fat content was significantly higher than control mice.These finding may suggest that the physiological regulations in energy budget and body mass are employed by small mammals to meet the environmental stress caused by different stochastic food restriction.Animals are able to increased fat storage when food is plentiful and then increase the capability to cope with lower food availability.关键词
基础代谢率/体重/限食/KM小鼠Key words
basal metabolic rate（BMR）/body mass/food restriction/KM mice分类
生物科学引用本文复制引用
陈可新,王守山,孟喜龙,王桂英,李玉保,马飞,赵志军..限食程度对KM小鼠体重和能量代谢的影响[J].聊城大学学报：自然科学版,2011,24(3):29-33,5.基金项目
国家自然基金项目 （）
山东省教育厅项目 （）
聊城大学博士科研启动基金 （）
