临床误诊误治2012，Vol.25Issue(1)：11-14,4.DOI:10.3969/j.issn.1002-3429.2012.01.005
骨髓呈再生障碍性贫血样表现的低增生性白血病
Hypocellular Acute Leukemia Characteriged by Aplastic Anemia in Bone Marrow
摘要
Abstract
Objective To discuss the key points of differential diagnosis between hypocellular acute leukemia and aplastic anemia to reduce misdiagnosis rate. Methods Retrospective analysis of a case of hypocellular acute leukemia was made. Results In this case, the patient suffered gum bleeding for 2 years continuously, and was admitted one month after echymosis in skin occurred. His bone marrow histology showed aplastic anemia for the first time. But it showed acute monocytic leukemia for the second time in bone marrow histology examination. After diagnosis of bone marrow histology and biopsy and flow cytometry, it was confirmed as hypocellular acute leukemia, and he was given HAG for courses of treatment. The bone marrow did not present complete remission, and the patient gave up treatment and was discharged. Conclusion The manifestation of hypocellular acute leukemia and aplastic anemia are similar, and sometimes it is difficult to differentiate. So we have to do several examinations including peripheral blood smear, bone marrow smear and biopsy, flow cytometry and cytogentics. And the bone marrow puncture should be done in different points in the patients. Synthetical diagnosis should be made to avoid misdiagnosis.关键词
白血病/贫血,再生障碍性/误诊/鉴别,诊断Key words
Hypocellular acute leukemia/ Aplastic anemia/ Diagnostic error/ Differential diagnosis分类
医药卫生引用本文复制引用
陈勤,汤屹,孟力..骨髓呈再生障碍性贫血样表现的低增生性白血病[J].临床误诊误治,2012,25(1):11-14,4.基金项目
湖北省自然科学基金(2005ABA150) （2005ABA150）
