临床误诊误治2012，Vol.25Issue(1)：23-26,4.DOI:10.3969/j.issn.1002-3429.2012.01.010
以骨转移症状首发的肺癌临床特征及误诊分析
Clinical Features and Misdiagnosis Analysis of Lung Cancer with Symptoms of Bone Metastases as the First Manifestation
何玉明 1李良平 1张海琳 1黄忠达1
作者信息
- 1. 443200 湖北枝江,枝江市人民医院肿瘤科
- 折叠
摘要
Abstract
Objective To discuss the clinical features of lung cancer with symptoms of bone metastases as the first manifestation and analyze misdiagnosis and prognosis factors. Methods The clinical records of SO lung cancer patients with symptoms of bone metastases as the first manifestation during June 2001 and June 2010 in our hospital were retrospectively analyzed. Results All 50 patients had bone pain, 20 suffered from neurologic symptoms and 6 had pathologic bone fracture. The main clinical features of bone metastases were multiple locations and osteolytic bone destruction. 46 cases were initially misdiagnosed, with a misdiagnosis rate of 92% , and the duration of the misdiagnosis period varied from 3 days to 3 months- The top 3 misdiagnosed diseases were lumbar disc herniation( LDH) , hyperostosis and primary bone tumors. Among the 50 cases, 46 were pathologically diagnosed, 2 were cytological diagnosed as having malignant tumors and 2 were diagnosed by imaging tests. The 1 -year survival rate of 50 patients was 10% with a mediam survival time of 4 months. Conclusion The main clinical features of lung cancer with symptoms of bone metastases as the first manifestation are multiple locations, osteolytic bone destruction, and high incidence rate of adenocarcinoma bone metastases. Because of the poor prognosis of bone metastases and high rate of misdiagnosis, clinicians should attach great importance to there features.关键词
肺肿瘤/肿瘤转移/骨肿瘤/误诊/椎间盘移位/骨质疏松Key words
Lung neoplasm/ Neoplasm metastasis/ Bone neoplasm/ Diagnostic error/ Intervertebral disk displacement/ Osteoporosis分类
医药卫生引用本文复制引用
何玉明,李良平,张海琳,黄忠达..以骨转移症状首发的肺癌临床特征及误诊分析[J].临床误诊误治,2012,25(1):23-26,4.
