临床误诊误治2012，Vol.25Issue(2)：27-29,3.DOI:10.3969/j.issn.1002-3429.2012.02.013
连续性血液透析滤过对血清半胱氨酸蛋白酶抑制剂C的影响
Influence of Continuous Hemodiafiltration on Serum Cystatin C
摘要
Abstract
Objective To observe the change of serum cystatin C in the process of continuous hemodiafiltration, and to find indicators to monitor renal function during continuous hemodiafiltration. Methods 52 patients with severe acute renal injury under went continuous blood filtration treatment, the values of both serum cystatin C and serum creatinine before and after blood filtration were recorded, compared and analyzed. Results The average serum cystatin C of the 52 cases before treatment was (6.87 ± 2. 11)μmol/L, 24, 48, 72 h after treatment it was (6.34 ± 1. 89)μmol/L, (6.08 ± 1.40) μmol/L, (5. 86 ±2.37) μmol/L, the av erage serum cystatin C before and after treatment showed no significant statistical difference (t = - 0. 364, - 0.286, - 0.367, P = 0.233, 0. 179, 0.154). The average serum creatinine before treatment was (732.00 ±59.64) μmol/L, 24, 48, 72 h after treatment it was (497. 00 ±41.31) μmol/L, (258. 00 ±45.69) μmol/L, (173. 00 ±55.27) μmol/L, the average serum creatinine before and after treatment showed no significant difference (t = 2.143, 2.576, 2.973, P = 0.035, 0.021, 0.010). Conclusion Continuous he modiafiltration therapy may not significantly affect the level of serum cystatin C, and serum cystatin C can been used as renal re placement therapy process indicators to monitor renal function.关键词
半胱氨酸蛋白酶抑制剂C/血液透析滤过/肾功能衰竭Key words
Cystain C/ Hemodiafiltration/ Kidney failure分类
医药卫生引用本文复制引用
虞燕波..连续性血液透析滤过对血清半胱氨酸蛋白酶抑制剂C的影响[J].临床误诊误治,2012,25(2):27-29,3.基金项目
国家自然科学基金项目(30901561) （30901561）
