老年医学与保健2012，Vol.18Issue(1)：15-18,4.DOI:10.3969/j.issn.1008-8296.2012-01-06
收缩功能正常心力衰竭患者血sST2、pro-BNP、超敏TNT水平测定的意义
Detection significance ofsST2,pro-BNP and high-sensitive troponin in patients with normal systolic function heart failure
摘要
Abstract
Objective The aim of this study was to investigate the role of sSt2, pro-BNP, high-sensitive troponin in diagnosis of normal systolic function heart failure in the patients. Methods The study group comprised 100 patients (E/A < 1, pro-BNP > 220 pg/mL) suffering from heart failure as treatment group, and 80 healthy persons as control group. Lipid levels (TC、LDL、 TG、 HDL), FBG, sST2, pro-BNP, high-sensitive troponin and echocardiography were measured, respectively. Results 1. Level of sST2, pro-BNP, high-sensitive troponin in the normal systolic function heart failure group were significantly higher than those in the control group (P<0.01). 2. With increase in the NYHA degree, levels of ST2, pro-BNP and high-sensitive troponin increased in the experiment group. 3. There was positive correlation between levels of sST2, pro-BNP, high-sensitive troponin and LEVDD, while negative correlation between levels of sST2, pro-BNP, high-sensitive troponin and E/A in the experiment group. 4. There was a linear correlation between levels of sST2, pro-BNP and high-sensitive troponin. Conclusion sST2, pro-BNP and high-sensitive troponin participate in the pathological and physiological processes of heart failure, which are important to diagnose the earlier normal systolic function heart failure.关键词
sST2/pro-BNP/超敏TNT/收缩功能正常心衰Key words
sST2/ Pro-BNP/ High-sensitive troponin/ Normal systolic function heart failure分类
医药卫生引用本文复制引用
葛剑力,江华,邵莉,张代富..收缩功能正常心力衰竭患者血sST2、pro-BNP、超敏TNT水平测定的意义[J].老年医学与保健,2012,18(1):15-18,4.基金项目
浦东新区卫生系统重点学科群建设 (PWZxkq2010-05)资助 （PWZxkq2010-05）
