护理学报2012，Vol.19Issue(4)：60-65,6.
重症肌无力患者病情复发或加重的影响因素分析
Multivariate Analysis of Recurrence or Exacerbation for Patients with Myasthenia Gravis
摘要
Abstract
Objective To identify the independent risk factors of recurrence or exacerbation for patients with myasthenia gravis (MG) and propose corresponding nursing measures. Methods The combination design of cross-sectional study and prospective descriptive study was adopt. Data including 30 variables affiliated to demographic characteristics, disease characters and symptoms and signs sections collected from the patients diagnosed as MG was analyzed. Then, the independent analyses of cross-sectional study and prospective descriptive study were performed respectively. Results Of the total, 158 and 18 patients were in adverse outcome respectively. In the multivariate analyses, four independent predictive factors were correlated with adverse outcome in non - hospitalization group: infection (OR: 4.564, 95%C/: 32.288-285.362), inappropriate treatment (OR: 1.855, 95%CI: 2.945~13.878), body discomfort (OR: 1.874, 95% CI: 2.915~14.565) and excessive fatigue(OR:1.864, 95% CI:2.983-13.932); two independent predictive factors were correlated with adverse outcome in hospitalization group: infection (OR: 2.619, 95%CI: 3.054~61.632) and emotion depress (OR: 2.684, 95%CI: 2.831~75.710). Conclusion Infection, inappropriate treatment, excessive fatigue and body discomfort are independent risk factors related with recurrence or exacerbation of MG in non-hospitalization. Infection and emotion depress are independent risk factors related with recurrence or exacerbation of MG in hospitalization. More attention should be attached to these risk factors in disease prevention and clinical administration.关键词
重症肌无力/加重/复发/危险因素Key words
myasthenia gravis/ exacerbation/ recurrence/ risk factor分类
医药卫生引用本文复制引用
杨云英,刘凤斌,侯政昆,朱爱利,饶秀珍,古彩红..重症肌无力患者病情复发或加重的影响因素分析[J].护理学报,2012,19(4):60-65,6.基金项目
"国医大师邓铁涛传承工作室建设"项目(A2100015),国家十一五科技支撑计划"疑难病中医干预及疗效评价研究"(2006BAI04A12) （A2100015）
