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局部晚期宫颈癌术前新辅助化疗52例的疗效分析

王全利 张必杰 唐艳 汤海霞 张莉 周丽

南京医科大学学报(自然科学版)2011,Vol.31Issue(11):1656-1659,4.
南京医科大学学报(自然科学版)2011,Vol.31Issue(11):1656-1659,4.

局部晚期宫颈癌术前新辅助化疗52例的疗效分析

The efficacy analysis of neoadjuvant chemotherapy used for 52 patient of locally advanced cervical cancer

王全利 1张必杰 2唐艳 1汤海霞 1张莉 1周丽1

作者信息

  • 1. 南通市中医院妇科,江苏南通226001
  • 2. 南通市肿瘤医院妇科,江苏南通226361
  • 折叠

摘要

Abstract

Objective; To investigate the clinical efficacy of neoadjuvant chemotherapy used for locally advanced cervical cancer . Patients. Methods: Total 52 cases of Ⅰ b2~ Ⅱ b cervical cancer were included. According to pathological types of the cancer cells,2 to 3 cycles of combined chemotherapy were used before surgery,then extensive hysterectomy and pelvic lymph node dissection would be done. Results; After preoperative chemotherapy,symptoms and signs of all patients were significantly improved,it created favor-able conditions for the radical surgery,total clinical effective rate was 92.5%,and surgery rate was 88.50%(46/52). Conclusion; The use of neoadjuvant chemotherapy for the locally advanced cervical cancer before surgery can alleviate clinical symptoms significantly, reduce size as well as the invaded area of the tumor,lower clinical stage and improve the surgery rate,reduce risk factors and the re-lapse rate,and it can be expected to extend 5-year survival.

关键词

宫颈癌/新辅助化疗/手术率

Key words

cervical cancer/neoadjuvant chemotherapy/surgery rate

分类

医药卫生

引用本文复制引用

王全利,张必杰,唐艳,汤海霞,张莉,周丽..局部晚期宫颈癌术前新辅助化疗52例的疗效分析[J].南京医科大学学报(自然科学版),2011,31(11):1656-1659,4.

南京医科大学学报(自然科学版)

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