南京医科大学学报（自然科学版）2011，Vol.31Issue(11)：1663-1666,4.
输卵管组织LIF及其受体LIFR的表达与输卵管妊娠的关系
The correlation between the occurrence of tubal pregnancy and the expression levels of LIF and LIFR in oviduct tissues
摘要
Abstract
Objective: To explore the correlation between the occurrence of tubal pregnancy and the expression level of leukemia inhibitory factor (LIF) and LIF receptor (LIFR). Methods; Semi-quantitative analysis of LIF and LIFR by immunohistochemistry was performed in 11 fallopian tubal tissues of non-pregnant group,and 36 of tubal pregnancy group,respectively. Results; The LIFR expression level in fallopian tubal epithelium cells of tubal pregnancy group was significantly higher than that of non-pregnant group. While the LIFR abundance in interstitial cells of tubal pregnancy group was significantly lower than that of non-pregnant group. How-ever, no significant difference of LIF abundance was found between two groups. Conclusion; Aberrant expression of LIFR in oviduct tissues might be involved in the ectopic implantation process of tubal pregnancy.关键词
输卵管妊娠/白血病抑制因子/白血病抑制因子受体Key words
tubal pregnancy/ LIF/ LIFR分类
医药卫生引用本文复制引用
李咏,孙丽洲,赵丹梅,欧阳俊,向梅,马文琴,吴超英,史文忠,唐正华..输卵管组织LIF及其受体LIFR的表达与输卵管妊娠的关系[J].南京医科大学学报（自然科学版）,2011,31(11):1663-1666,4.基金项目
江苏省自然科学基金(BK2010583),常州市科技局科研基金资助(CS20092013) （BK2010583）
