南京医科大学学报（自然科学版）2011，Vol.31Issue(11)：1670-1673,4.
6月龄以下小婴儿川崎病43例临床分析
Clinical analysis of 43 cases of Kawasaki disease of young infants aged under 6 months
张雅媛 1钱小青 1李娟 1俞海国 1郭翼红 1马慧慧1
作者信息
- 1. 南京医科大学附属南京儿童医院风湿免疫科,江苏南京210008
- 折叠
摘要
Abstract
Objective:To summarize clinical characteristics of Kawasaki disease (KD) in infants younger than 6 months and ex-plore indices for early diagnosis. Methods; Retrospective data from 43 cases of KD in infants younger than 6 months were collected in Nanjing Children's Hospital from March 2005 to February 2009, and compared with 238 cases of KD in children older than 6 months in the same period. Results: Among 43 cases of KD in infants younger than 6 months, male-female ratio was 2.31:1. Com-pared with 238 cases of KD in children older than 6 months, the incidence of some clinical features, such as BCC vaccination ery-thema, symptoms in digestive system and nervous system at acute period were increased significantly (P < 0.05), while cervical lym-phadenopathy was absent in 43 cases of KD in infants younger than 6 months. The levels of neutrophils (N%), platelet (PLT), ery-throcyte sedimentation rate(ESR) and lactate dehydrogenase(LDH) in infants were higher (P < 0.05) and the level of Hb was lower (P < 0.05) than children. The incidence of incomplete KD cases and coronary artery aneurysm in infants increased statistically (P < 0.05). Conclusion; Incomplete KD cases and coronary artery aneurysm are more common in infants younger than 6 months. Exami-nation of coronary artery abnormalities, BCG vaccination erythema, symptoms in digestive system and nervous system and the levels of N%, PLT, ESR, LDH and Hb in time would be helpful for early diagnosis.关键词
小婴儿/川崎病/不完全川崎病/冠脉损害/早期诊断Key words
young infant/ Kawasaki disease/ incomplete Kawasaki disease/ coronary artery lesions/ early diagnosis分类
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张雅媛,钱小青,李娟,俞海国,郭翼红,马慧慧..6月龄以下小婴儿川崎病43例临床分析[J].南京医科大学学报（自然科学版）,2011,31(11):1670-1673,4.
