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宫颈癌组织差异表达基因的检测及分析

王有良 丁显平

四川大学学报(自然科学版)2011,Vol.48Issue(6):1449-1455,7.
四川大学学报(自然科学版)2011,Vol.48Issue(6):1449-1455,7.DOI:10.3969/j.issn.0490-6756.2011.06.040

宫颈癌组织差异表达基因的检测及分析

The detection and analysis of differentially expressed genes in Cervical cancer tissues

王有良 1丁显平2

作者信息

  • 1. 四川大学生命科学学院生物资源与生态环境教育部重点实验室,遗传医学研究所,成都610064
  • 2. 彭州市人民医院,彭州611930
  • 折叠

摘要

Abstract

The human gene expression of cervical cancers infected with HPVI6 and their perienchyma were analyzed with Roche NimbleGen system. The analysis demonstrated that there are 673 differential expressed genes between cervical cancers and their normal cervical tissues (TvsF). Compared to normal cervical tissues, the expression of 261 genes was up-regulated and expression of 412 genes was down regulated in cervical cancers. All of the differential expressed genes involved in the signal transduction, metabolism, immunity response, protein biosynthesis and ESTs.

关键词

宫颈癌/人乳头瘤病毒/基因表达/基因芯片

Key words

cervical carcinoma/human papillomavirus/gene expression/cDNA microarray

分类

生物科学

引用本文复制引用

王有良,丁显平..宫颈癌组织差异表达基因的检测及分析[J].四川大学学报(自然科学版),2011,48(6):1449-1455,7.

基金项目

重庆市医药卫生攻关项目(渝卫科0802344) (渝卫科0802344)

四川大学学报(自然科学版)

OA北大核心CSCDCSTPCD

0490-6756

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