四川大学学报(自然科学版)2011,Vol.48Issue(6):1449-1455,7.DOI:10.3969/j.issn.0490-6756.2011.06.040
宫颈癌组织差异表达基因的检测及分析
The detection and analysis of differentially expressed genes in Cervical cancer tissues
摘要
Abstract
The human gene expression of cervical cancers infected with HPVI6 and their perienchyma were analyzed with Roche NimbleGen system. The analysis demonstrated that there are 673 differential expressed genes between cervical cancers and their normal cervical tissues (TvsF). Compared to normal cervical tissues, the expression of 261 genes was up-regulated and expression of 412 genes was down regulated in cervical cancers. All of the differential expressed genes involved in the signal transduction, metabolism, immunity response, protein biosynthesis and ESTs.关键词
宫颈癌/人乳头瘤病毒/基因表达/基因芯片Key words
cervical carcinoma/human papillomavirus/gene expression/cDNA microarray分类
生物科学引用本文复制引用
王有良,丁显平..宫颈癌组织差异表达基因的检测及分析[J].四川大学学报(自然科学版),2011,48(6):1449-1455,7.基金项目
重庆市医药卫生攻关项目(渝卫科0802344) (渝卫科0802344)