摘要
Abstract
Objective To explore the daytime continuous renal replacement therapy (CRRT) severe acute hyponatremia the efficacy, safety. Methods In our jan 2005 ~2010 December 17 cases of severe acute hyponatremia hospitalized patients use jinbao Prisma line continuous renal replacement therapy (CVVH), daily therapy for eight hours, 3 consecutive days, replacement fluids before using dilution and displacement liquid flow 4L/h, patients serum sodium before treatment level 112. 5 mmol/L, plus or minus 4. 0 day 1 set displacement liquid sodium concentrations than serum sodium high level 10 ~ 14 mmol/L, the first two or three days set displacement liquid treatment end sodium concentrations than actual serum sodium high level 9 ~ 12mmol/L, 6-9 mmol/L. Results All patients time of 3 days, 8 hours a day, all successfully completed, serum sodium by before treatment 112. 5 mmol/L plus or minus 4. 0 rose to 140. 2 mmol/L, plus or minus 2. 8 serum osmotic pressure return to normal gradually, neuropsychiatric symptoms improved obviously by before treatment, Glasgow score (8. 3 ± 1. 7) rise to 14. 5 plus or minus 0. 6. Conclusion CBP treatment of acute serious hyponatremia avoid the traditional methods make serum sodium rises too fast or slow shortcomings, can adjust blood sodium correct according to target speed, group study shows that CBP treatment of acute serious hyponatremia definite effect, high success rate, safety, can yet be regarded as severe acute hyponatremia important therapy.关键词
连续性肾替代治疗/低钠血症Key words
continuous renal replacement therapy/hyponatremia分类
医药卫生
